producing a high proportion of males to females instead of an equal ratio 2. This distortion results from 'sex conversion': male ES cells that are injected into a female blastocyst may drive the ...

Approximately five days post fertilization (dpf), the blastocyst develops. The inner cell mass gives rise to the fetus ... These invading cells remodel spiral arteries to reroute parental blood to the ...

This process, known as blastocyst complementation, involves injecting rat stem cells into mouse blastocysts—early-stage embryos lacking the ability to develop a pancreas due to genetic mutations.