The researchers found that the ZO-1 protein directs YB-1 to form beneficial stress granules. Stress granules are clusters of proteins that assemble inside cells exposed to stressful conditions ...

We are interested in mechanisms that regulate RNA Stress Granule (SG) and Processing Body (P-body) formation in cells. These two types of RNA granules aggregate translationally-silenced mRNAs and ...

GA, UNITED STATES, March 3, 2025 /EINPresswire / -- A comprehensive review provides new insights into the pivotal role of stress granules (SGs) in cellular stress responses and their profound ...

Recent work has shown us that G3BP nucleation of stress granules in the absence of virus infection activates PKR, resulting in phosphorylation of eIF2alpha and activation of NF-kB and JNK signal ...

Scientists are still trying to figure out the exact reason behind it, but recent research has highlighted one possible factor stress granules (SGs). These are tiny clumps of proteins and RNA that ...

As a result, some TDP-43 was released from the cell nucleus into the cytosol, where it accumulated in so-called stress granules. The paper is published in the journal Nature Chemical Biology.