研究结论和讨论部分表明，ProPPr 方法适用于 FFPE 脑组织，能够无偏地发现局部蛋白质组，为 tau 蛋白病的潜在蛋白质组学景观提供有价值的见解，有助于揭示 tau 病理的分子机制。研究发现的这些与 tau ...

Alzheimer’s disease, a devastating neurodegenerative disorder, is closely linked to the accumulation of tau protein in the ...

The discoveries in this research pertain to diseases that accumulate 4R tau. Merging advanced techniques such as transmission electron microscopy and molecular dynamics simulations with in-vitro ...