本研究聚焦于解决AAV载体包装容量有限导致的细胞类型特异性大基因载荷递送难题，通过空间基因组学技术揭示了AAV基因组间的转录串扰机制，并利用该机制实现了系统给药的细胞类型特异性基因编辑，为基因治疗提供了新策略。 基因治疗领域一直面临着一个 ...

Four gene-therapy clinical trials starting in 2020 will make use of improved delivery viruses from Jichi Medical University to tackle serious neurological disorders. Adeno-associated viral (AAV ...

Gene therapy, a technique that is revolutionizing the treatment of multiple genetic conditions, including eye and muscle diseases and blood disorders, requires efficient and specific delivery of ...