AMP-activated protein kinase (AMPK) regulates metabolism by sensing changes in the AMP:ATP ratio in eukaryotic cells. The binding of AMP to AMPK and activation of its Ser/Thr protein-kinase domain ...

Transcriptional profiling of pathways pertinent to glycolysis, Oxphos and mitochondrial structure and function ... showed about 15% of them to be AMPK- and/or Myc-dependent in their steady state.