The APC gene was discovered by Kimmel Cancer Center researchers in 1991, and mutations in APC occur in over 90% of all colorectal tumors. "HMGA1 functions like a molecular 'key' that 'opens ...
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Hereditary colorectal cancer: Researchers reclassify a large proportion of leading gene variants as benign"The gene-specific classification criteria we developed have now allowed us to reclassify a significant proportion of VUS of the APC gene into a medically relevant category," says Prof. Aretz ...
Colon cancer has been on the rise in Americans under 50 for the last three decades, but it’s not exactly clear why. Researchers suspect poor diet, obesity, sedentary lifestyles, environmental ...
Authors who publish open access in Gene Therapy are required to pay an article processing charge (APC). The APC price will be determined from the date on which the article is accepted for publication.
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