An antibody that reacts with acetylated histones H3 and H4 immunoprecipitated chromatin containing the gelsolin promoter in the TSA-treated bladder cancer cells, but not in nontreated cells.

Looking to improve the quality of tools for discovering genomic regulatory regions, researchers at the National Institutes of Health combined Chromatin immunoprecipitation (ChIP) of hyper-acetylated ...

to bind to acetylated histones—proteins that help organize DNA—to act on genes promoting cell survival. Moreover, in breast cancer, BET proteins trigger a runaway transcription cycle ...

suggesting that a chromatin-based counting mechanism restricts X inactivation to cells with more than one X chromosome (Human Molecular Genetics, 12:1783-1790, August 1, 2003). O'Neill et al.