Achondroplasia is a genetic skeletal condition that results in disproportionately short stature and health complications throughout life, such as an exaggerated inward curve of the lumbar spine ...

At the core of achondroplasia's pathology lies the hyperactivation of FGFR3, which impairs not only the growth of long bones but also affects cranial, spinal, and vertebral development.

The mutational spectrum of fibroblast growth factor receptor 3 (FGFR3) in individuals with achondroplasia. In humans, the mutations associated with achondroplasia patients are mainly located in ...

Ascendis Pharma A/S (Nasdaq: ASND) today announced it will share the latest data from its hypoparathyroidism, achondroplasia, and growth hormone deficiency (GHD) programs during ESPE & ESE 2025, the ...

Achondroplasia limits bone growth in the limbs and leads to abnormal growth in the spine and skull. Some choose to undergo limb-lengthening surgery. Dr Evelyn Kuong is an orthopaedic surgeon in ...