Filopodia help cells move but also aid cancer spread. Scientists have revealed how fascin proteins build these structures, ...
Phys.org on MSN17d
Scientists finally know how cells build a structure that lets them migrate. What they learned could help treat cancerThe findings, published in Nature Structural & Molecular Biology ... “We saw how the structure of fascin gives rise to its function as an actin bundler and figured out the detailed chemistry of its ...
Forget the traditional tubular shape—researchers are investigating a pearl-on-a-string formation for axons, unlocking new ...
The findings, published in Nature Structural & Molecular Biology ... "We saw how the structure of fascin gives rise to its function as an actin bundler and figured out the detailed chemistry ...
To gain more molecular insight into this process, we focused on actin proteins." Actin is a component of the cell's structure ...
Scientists reveal how filopodia help cancer spread. The breakthrough could improve treatments that stop cancer cells from invading tissues.
The mechanism of molecular motors involves a cyclic interaction between the motor domain and the cytoskeletal filament (actin or microtubule). ATP hydrolysis induces conformational changes in the ...
The ‘Actin-based molecular machines’ group of Academy Professor Pekka ... and structural biology methods to reveal how structure and dynamics of the actin cytoskeleton are regulated in various ...
Pekka Lappalainen, Professor Pekka carried out his PhD-thesis work at EMBL, Heidelberg, Germany, where he studied the structure and function ... in understanding the molecular machines (proteins) ...
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