Adenosine also plays important roles in regulating neuronal signaling in the direct pathway neurons. Adenosine A1 receptors are expressed presynaptically where they compete with A2A receptors through ...

The adenosine pathway has emerged as an attractive target for immuno-oncology R&D because it is thought to reduce the activity of misfunctioning regulatory T-cells that inhibit the immune response ...

To ensure the community can capitalize on this, the 2nd Annual Adenosine-Pathway Targeted Cancer Immunotherapy Summit will be returning this June (20 – 22) in Boston, MA – dedicated to ...

In intact mouse models, adenosine significantly reduced and DPCPX significantly increased the power of harmaline-induced tremor compared with baseline tremor in the same mouse (P <0.05 for both).

Inozyme Pharma is a clinical-stage biopharmaceutical company dedicated to developing innovative therapeutics that target the PPi-Adenosine Pathway, a key regulator of bone health and blood vessel ...

A live webcast of the fireside chat can be accessed from the Investor Relations section of Inozyme’s website under events, where a replay of the event will also be available for a limited time.

We are experts in the PPi-Adenosine Pathway, where the ENPP1 enzyme generates inorganic pyrophosphate (PPi), which regulates mineralization, and adenosine, which controls intimal proliferation ...