We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...

Adenosine is a short-acting endogenous molecule that is a purine nucleoside. The half-life is 6 seconds. Adenosine receptor activation results in multiple different actions depending on the location.

The reaction product is adenosine diphosphate (ADP), and the phosphate group either ends up as orthophosphate ... Walker first determined the amino acid sequence of this enzyme, and then elaborated ...

Adenosine is widely used as an antiarrhythmic agent for the investigation and management of both narrow complex and, less often, broad complex tachycardias. Over the past 10 years or so, reports of ...

It differs from adenosine by the absence of an amino group at the 6 position of the purine ring ... and structural biology approaches will provide a more comprehensive understanding of the complex ...

This paper provides a valuable contribution to our understanding of how adenosine acts as a signal of nutrient insufficiency and extends this idea to suggest that adenosine is released by ...

Objectives To compare fractional flow reserve (FFR) obtained during maximal hyperaemia by Intravenous (IV) ATP and adenosine. Methods 23 patients with 25 lesions underwent determination of FFR with ...