the intervening sequences in the DNA strand appear as loops, i.e., the corresponding segments lack counterparts in the RNA. The hybrid could be directly visualized in the electron microscope.

This cassette is then transferred to the adenovirus vector plasmid (pAdeno X, Clontech Laboratories or pAd5F35, The Journal of Gene Medicine Volume 6, Issue 6 , Pages 631 - 641). The adenovirus vector ...

To address this bottleneck, Seymour and colleagues developed a new way to manufacture rAAV using the ‘helper’ adenovirus technique. “We focused on helper-adenovirus production as it is ...