As an intermediate between traditional 2D in vitro cell cultures and animal models, organoids are a useful tool for several applications. The complexity of the TME in vivo limits the conclusions that ...

“An effective disease model is absolutely fundamental,” says Duchen. “You can’t do anything without one.” As mitochondria are critical for healthy cell function, when they fail, the ...

This page provides educational resources, events, news and products related to advanced cell models. Content will cover aspects from the creation of organoids and organs-on-chips, to how they are ...

The new cell models displayed ... For more information on how to enhance your research with advanced biological models, visit ATCC online. Guidance for Industry: Drug Interaction Studies-Study ...

The Advanced Cell Engineering and 3D Models (ACE-3M) Core provides established services offered previously by AIM and C-BASS cores plus new expanded capabilities for tumor organoids grown in 3D ...

PDXO 3D Culture in Matrigel. Maintenance and/or expansion of active PDX-derived organoids growing in Matrigel. PDO and PDXO-PDX derived tumor organoid culture. Generation of tumor organoid models from ...

Scientists create models by transplanting human brain cells culled from stem cells into the brains of animals such as mice, ...

The course explores concepts and methods in advanced molecular cell biology and protein biochemistry. Molecular mechanisms responsible for the signalling and biochemical responses of cells will be ...

With the advent of cost-effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant ...