What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

Deciphering the structures of proteins is critical to structural drug design. Cryo-electron microscopy (cryo-EM) now offers a radically different way to study the structure of large biomolecules ...

Purdue University-connected startup Molecular Intelligence supports research scientists in bioengineering, medical science and pharmaceutical companies who use cryo-EM to determine 3D structures of ...

The following microscopes are available for use in the CryoEm Core. The Thermo Scientific™ Aquilos™ 2 Cryo-FIB is the first cryo-DualBeam™ (focused ion beam/scanning electron microscope) system ...

Cryo-electron microscopy of tau filaments from individuals with mutant V337M and R406W tau show the Alzheimer fold. The apical–basal polarity of epithelial cells depends on mutual antagonism ...

It enables ambient temperature and cryo-electron microscopy of single particle or tomography samples to obtain preliminary data prior to more detailed analysis on higher specification TEMs. FEI Tecnai ...

The Cryo-Electron Microscopy Facility (CEMF) advances the overall UAB mission by supporting the application of cryo-EM in making new scientific discoveries. We provide access and training in the use ...

The University of Colorado Boulder Biochemistry Department's Krios Electron Microscopy facility (BioKEM) offers single particle cryo-EM and cryo tomography of plunge-frozen samples. The BioKEM ...

The correlative stage was developed out of the necessity for a tool that uses fluorescence microscopy to help localise structures of interest in samples for high-resolution cryo-electron microscopy ...

But how GGCX facilitates this reaction has been unclear. To answer this question, Dr. Qi and his colleagues used cryo-electron microscopy (cryo-EM). By freezing molecules at temperatures around ...