More information: Charlotte E. Moss et al, Aging-related defects in macrophage function are driven by MYC and USF1 ...
In aging mice, senescent cells in the choroid plexus recruited circulating macrophages. These immune cells released a protease, cathepsin S, that chewed up claudin 1, part of the glue that seals ...
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Why does cancer risk skyrocket as we age? How ‘inflammaging’ is the new tool to end the diseaseFinding ways to control and redirect macrophages will have “a profound impact on cancer and potentially even aging,” he says. Dr. Yara Abdou, an assistant professor of oncology at the ...
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Ferroptosis contributes to immunosuppressionIron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.
Telomere Length and Aging Telomeres, protective caps at the ... A clinical trial involving 161 participants revealed that the intake of Macrophage Activating Factor resulted in remarkable telomere ...
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