For instance, in normal, healthy mice, the agouti genes are kept in the "off" position by the epigenome, which attaches methyl groups to the corresponding regions of DNA, resulting in the DNA's ...

One, the agouti-related protein (AGRP) and neuropeptide Y (NPY) neurons, stimulates hunger, while the other, ...

In the brown mice, this element is methylated and, therefore, silenced. But in the yellow mice, it isn’t methylated, meaning that these animals overexpress Agouti signaling protein in many tissues, ...

Within the ARC, there are orexigenic coexpressing neuropeptide Y/Agouti gene-related protein (NPY/AgRP) and anorexigenic pro-opiomelanocortin (POMC)/cocaine- and amphetamine-related transcript ...

The best characterized pathways are the orexigenic neuropeptide Y/Agouti-related protein and the anorexigenic pro-opiomelanocortin/cocaine- and amphetamine-related transcript neurons in the ...