This suggests that a preexistent partial hormonal resistance in young infants might aggravate the impaired renal aldosterone sensitivity secondary to urinary infections. This putative aldosterone ...

Renal hypoperfusion occurs as a result of reduced cardiac output, resulting in the activation of the renin–angiotensin–aldosterone system, which compensates for the hypoperfusion. However ...

The investigational aldosterone synthase inhibitor lorundrostat effectively lowered 24-hour BP for adults with well-treated, ...

chronic kidney disease (CKD), the metabolic syndrome, and diabetes mellitus (Schrier, R. W. et al. Clin. J. Am. Soc. Nephrol. in press). The finding that angiotensin II and aldosterone are ...

In March 2025, Shandong Suncadia Medicine Co., Ltd. conducted a phase II Clinical Study of Efficacy and Safety of HRS-1780 ...

Aldosterone is known to bind to these receptors in the kidney and cardiovascular system, increasing blood pressure through increasing sodium reabsorption and probably other mechanisms. The drug is ...

Aldosterone antagonists (spironolactone ... New York Heart Association functional class IV symptoms, preserved renal function and a normal potassium concentration. Spironolactone was investigated ...

It suppresses the renin-angiotensin-aldosterone system ... Postsympathectomy. Renal or hepatic impairment. Dialysis (esp. high-flux membrane). Gout. Asthma. SLE. Acute myopia.

For example, kidney cancer can spread to the adrenal glands ... The hormones include: cortisol which helps control the blood pressure, blood sugar levels, immune system and stress response aldosterone ...