Significant alterations in the structure and cellular composition of the distal lung are a defining characteristic of ...
The cells that cause the lung damage develop from ... More information: Yinshan Fang et al, RUNX2 promotes fibrosis via an ...
Savara Inc. (Nasdaq: SVRA) (the Company), a clinical stage biopharmaceutical company focused on rare respiratory diseases, ...
England FE, Bordeu I, Ng ME, Bang J, Kim B, Choi J, Cardoso EC, Koo BK, Simons BD#, Lee JH#. Sustained NF-kB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor ...
The patients’ cells, however, were unresponsive to CCL-2 and meandered ... the researchers found a decreased number of alveolar macrophages in their patients’ bronchoalveolar lavage samples. These ...
More information: Jimmy Tsz Hang Lee et al, Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID-19, Nature ...
In a healthy lung, excess surfactant is cleared and digested by immune cells called alveolar macrophages. Alveolar macrophages need to be stimulated by granulocyte-macrophage colony-stimulating ...
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