Significant alterations in the structure and cellular composition of the distal lung are a defining characteristic of ...

England FE, Bordeu I, Ng ME, Bang J, Kim B, Choi J, Cardoso EC, Koo BK, Simons BD#, Lee JH#. Sustained NF-kB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor ...

Savara Inc. (Nasdaq: SVRA) (the Company), a clinical stage biopharmaceutical company focused on rare respiratory diseases, ...

The patients’ cells, however, were unresponsive to CCL-2 and meandered directionless around the chamber. Consistent with lung surfactant build up in the children’s lungs and the monocyte migration ...

Alveolar macrophages (AMs) are specialized resident macrophages tasked with safeguarding the lower respiratory tract. The study reveals that AMs utilize cell division control protein 42 (CDC42 ...

Martin Hemberg. More information: Jimmy Tsz Hang Lee et al, Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID ...