Team behind tool hope to dramatically reduce the experimental workload of scientists using directed evolution to develop ...

This process, known as condensation or dehydration synthesis, results in the formation of a linear chain of amino acids. The sequence of amino acids in a protein, known as its primary structure, ...

or at alterations causing complex changes in the amino acid sequence (complex_aae). MutationTaster can be used via an intuitive web interface to analyze single mutations as well as in batch mode.

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

It seems that each amino acid is specified by a triplet of bases, and that triplets are read in simple sequence ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...

Scientists have shown that a sequence of just three amino acids may reduce the severity of psoriasis, when applied topically in an emollient cream. Birmingham scientists have shown that a sequence ...