Diabetes affects millions worldwide, often triggering complications such as insulin resistance and fatty liver disease. To ...

Mammalian AMP-activated protein kinase (AMPK) was discovered as a protein kinase that switches off lipid synthesis. The yeast orthologue, the SNF1 complex, was discovered in screens for mutations ...

This milestone, achieved in collaboration with Eli Lilly and Company (Lilly), targets a specific isoform of AMP-activated protein kinase (AMPK) for the treatment of cardiometabolic diseases.

Type 2 diabetes mellitus (T2DM) is a prevalent yet complex metabolic disorder that has shown a rising incidence over the past few decades. Recent research has identified flavonoids as compounds ...

AMP-activated protein kinase (AMPK) activity and gene expression were determined by quantitative reverse transcriptase-PCR and western blotting in search for mechanism of the reprogramming.