In AD, a small peptide, amyloid β-protein (Aβ), forms long, insoluble amyloid fibrils, which accumulate in spherical microscopic deposits known as senile plaques. However, the relevance of these ...

Figure 1: Imaging of amyloid-β deposits in the live mouse. Figure 3: In vivo imaging of amyloid-β deposits in 20-month-old homozygous PDAPP mice. Immunostaining with biotinylated or ...

“Structure Dependent Inhibition of b-Fibrillogenesis by Melatonin,” M. Pappolla, P. Bozner, C. Soto, M. Zagorski, H. Shao, N. K. Robakis, B. Frangione, and J ...

The study, titled "Effects of amyloid-β-mimicking peptide hydrogel matrix on neuronal ... step towards unraveling the mysteries of the b-amyloid-like environment which can be found in AD and ...

Franco Cavaleri, B.Sc., Ph.D.c, a distinguished biomedical research scientist and CEO of Biologic Pharmamedical Research and Manufacturing, has published a pioneering study that reexamines the role of ...