As AAV vector applications in gene therapy continue to expand, the need for precise and reliable tools to support research and development become increasingly critical. Two fundamental aspects of AAV ...

It produces data from a single assay, such as the percentage of full capsids, vector genome titer, and capsid titer ... and ligation: Antibody probes with tethered oligos bound AAV capsids.

While asymptomatic, these infections trigger the generation of neutralizing anti-AAV antibodies that can ... to the presence of the AAV vector capsid or its cargo can also hamper therapeutic ...

addressing the exclusion of patients with preexisting anti-AAV antibodies. Severe hemophilia A is caused by a genetic absence or variant in genes needed to produce blood-clotting factor VIII ...