The ability of an antiemetic agent to provide such protection depends on its half-life and its affinity for binding to the serotonin receptor. [30] ...

As a result of these guidelines, and in an attempt to reduce the overall cost of antiemetic therapy, many institutions have adopted strategies to reduce the total dose of 5-HT3-receptor antagonists.

Serotonin receptors of the 5-HT3 type are present ... It is not certain whether ondansetron’s antiemetic action is mediated centrally, peripherally, or in both sites. However, cytotoxic ...

Antiemetic drugs are used to treat nausea ... serotonin (a chemical neurotransmitter in the brain) from binding to receptors in the gut and CTZ, which is the area of the brain involved in ...

Serotonin receptors of the 5-HT3 type are present ... It is not certain whether ondansetron’s antiemetic action is mediated centrally, peripherally, or in both sites. However, cytotoxic ...