Moreover, OPC-14597 shares some characteristics of other atypical antipsychotics with respect ... the known molecular isoforms of the dopamine receptors in several transfection systems, as well ...

Significant weight gain is a common side effect of many psychiatric medications. Fortunately, there are options for those who ...

Previous attempts to selectively modulate muscarinic receptors by targeting the acetylcholine ... had activity in rodent models predictive of antipsychotic efficacy. It attenuated conditioned ...

such as the 5-HT 1A receptor, are considered to mediate the ability of antipsychotic drugs to enhance cognition. On the other hand, treatment with some atypical agents, such as risperidone ...

Recently, second-generation antipsychotics (SGAs), olanzapine plus fluoxetine, quetiapine extended release and aripiprazole have clearly demonstrated efficacy in the treatment of MDD patients ...

antipsychotic drugs targeted dopamine and were given to patients in form of pills, liquids, and injections since 1950s, ...