This is a wiring diagram that [Soranne] put together when developing a method of programming PIC microcontrollers using an Arduino board. You can see that he takes care of the 12V issue by ...

including the humble Arduino Uno. Miraculously, the Uno processed the network in an impressively fast prediction time of 114.4 μsec! Whilst we did not test the code on an MCU, we just happened to ...