Background: The Food and Drug Administration-approved argatroban dose for heparin-induced thrombocytopenia (HIT) is 2 µg/kg/min (0.5 µg/kg/min in hepatic impairment), adjusted to achieve ...

Of 313 patients administered argatroban during a 33-month period at Massachusetts General Hospital, 39 received therapy for presumed or previous HIT following CABG surgery. Demographic and ...