they transitioned the astrocytes to a pathogenic state by adding microglia-derived cytokines, which are the molecular cues that induce reactivity in neurodegenerative diseases. 2 Using this system to ...

Astrocytes are star-shaped glial cells in ... "With our colleagues at AbbVie Inc, we also studied progression of microglia, endothelial, and neuronal cells in AD," added Das.

Microglia phagocytose astrocyte end feet which is one of the components of BBB. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!

This analysis also visualized other cell types near plaques, for example astrocytes and vascular cells. The scientists are studying those now, Gate told Alzforum (image below). Do mobilized microglia ...

Astrocytes are notoriously two-faced—calmly coddling neurons one minute, then ruthlessly consuming their synapses the next. Why these dramatic mood swings? Blame the EphA4 receptor, according to a ...

Differentiation of iPSCs into neurons, astrocytes, microglia allow us to analyze aberrant gene and protein expression, function and metabolism in developing and maturing human brain before the disease ...

Tyrosine kinase 2 (TYK2), expressed in astrocytes and microglia, is involved in the activation of pathways triggered by proinflammatory cytokines, such as IL-23, IL-12 and type I interferons (IFNs), ...

Differentiation of iPSCs into neurons, astrocytes and microglia allow us to analyze aberrant gene and protein expression, function and metabolism in developing and maturing human brain well before the ...