In brief, autophagy is a ubiquitous process in eukaryotic cells that results in the breakdown of cytoplasm within the lysosome in response ... aspect of many autophagic processes.

De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the University of Vermont visited de Duve´s laboratory. An experienced ...

Autolysosomes then undergo ALR and lysosome biogenesis mediated by TFEB. ALR, autophagic lysosome reformation; ER, endoplasmic reticulum; ESCRT, endosomal sorting complexes required for transport ...

They assessed the optical performance of activatable organic RTP probes across a range of biological imaging and biosensing applications, including lysosome-targeted two-photon imaging ...

The proton levels or pH inside the autophagic vesicles changes from 6-6.5 to 4.5 as we go from autophagosomes to autolysosomes to lysosomes. Therefore, pH serves as an indicator for identifying ...