Brain-derived neurotrophic factor (BDNF) has an important role in supporting neuronal survival, which has encouraged studies of its therapeutic potential for neurodegenerative disorders such as ...

Moreover, it has been reported that higher brain BDNF expression is associated with slower cognitive decline in older adults.

This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

The Immense Importance of Brain-Derived Neurotrophic Factor Crossing the Blood-Brain Barrier According to research undertaken by Iughetti et al. (2011), the central nervous system and the ...

In young mice, the adipose-to-brain crosstalk helps sustain cognitive health by ensuring adequate BDNF production. However, ...

However, in aged mice, a deficiency of adipose 11β-HSD1 leads to insensitivity to steroid hormones, which in turn decreases the expression of adipose CX3CL1 and subsequently reduces brain BDNF ...