This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

Brain-derived neurotrophic factor (BDNF) has an important role in supporting neuronal survival, which has encouraged studies of its therapeutic potential for neurodegenerative disorders such as ...

However, in aged mice, a deficiency of adipose 11β-HSD1 leads to insensitivity to steroid hormones, which in turn decreases the expression of adipose CX3CL1 and subsequently reduces brain BDNF ...

The Immense Importance of Brain-Derived Neurotrophic Factor Crossing the Blood-Brain Barrier According to research undertaken by Iughetti et al. (2011), the central nervous system and the ...

In young mice, the adipose-to-brain crosstalk helps sustain cognitive health by ensuring adequate BDNF production. However, ...