Somatic test results were available for 280 men whose cancer had spread elsewhere. Overall, 31 (11%) had an identifiable BRCA2 genetic variant. Of these, 16 (6%) were confirmed germline and 11 (4% ...

A 2013 New York Times op-ed in which Angelina Jolie revealed she’d had a preventive double mastectomy because of her own BRCA mutation drove many women to seek DNA tests themselves. The BRCA ...

Ounce of Prevention is a weekly column which presents recommendations for preventative services derived from The United ...

The task force identified fair evidence that, without substantial family histories, women are at low risk for developing BRCA-mutation ... so that appropriate genetic testing can be recommended.

With cancer cases projected to rise by 77% to 35 million by 2050, understanding genetic predisposition has become increasingly important. In India, where one in nine people is projected to face a ...

“Genetic testing empowers patients to get the best ... “PARP inhibitors have improved overall survival for individuals with a BRCA mutation who take it as maintenance therapy after completing ...

The main indications for the non-BRCA patients to receive genetic testing included a personal history of breast cancer (51%) or a positive family history (27%). The risk-reducing surgeries that ...

We identified the breast cancer gene BRCA2, which enabled families with a history of breast cancer to be assessed for future risk, and laid the groundwork for developing novel forms of therapy for ...

We applied the principle of synthetic lethality to discover a novel strategy for cancer treatment for patients with BRCA1 or BRCA2 gene mutations. We demonstrated that drugs called PARP inhibitors ...

Jewish people in England are being invited to take part in a gene testing programme to identify carriers of BRCA mutations that elevate their risk of breast cancer. The NHS Jewish BRCA Testing ...

A woman who discovered she had breast cancer after a chance reading of a newspaper article is warning others with Jewish heritage of the increased risk. | ITV News Central ...