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BRCA1 gene mutations may not be key to prostate cancer initiation, as previously thoughtincluding cancer cells, to repair DNA damage, in men with BRCA1 genetic variants, say the researchers. A linked editorial suggests that the findings pave the way for greater refinement of genetic ...
BRCA1 and BRCA2 genes play a crucial role in repairing damaged DNA. Mutations in BRCA1 and BRCA2 substantially increase the likelihood of breast and ovarian cancer, respectively. This new research ...
including cancer cells, to repair DNA damage, in men with BRCA1 genetic variants, say the researchers. A linked editorial suggests that the findings pave the way for greater refinement of genetic ...
Whalen, Ph.D., poses a new explanation for how cancer-fighting drugs attack and destroy BRCA1 and BRCA2 tumor cells. Their work, published in Nature Cancer, illustrates how a small DNA nick—a ...
A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...
Opens in a new tab or window We followed 25,811 females and 480 males diagnosed with BC and tested for germline BRCA1/BRCA2 PVs in NHS Clinical Genetics centers in England between 1995 and 2019 ...
The BRCA1 (breast cancer gene one ... The PIK3CA gene gives instructions to make a protein that’s important for many cell functions. A PIK3CA mutation isn’t inherited – you can’t pass ...
Cells normally use highly accurate mechanisms to fix these breaks, but some cancers -- particularly those arising from BRCA1 or BRCA2 mutations, such as certain breast and ovarian cancers -- lack ...
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