People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...

Breast cancer survivors carrying BRCA1 and BRCA2 gene variants had a 48% overall lower risk of death after undergoing the surgery, which is known as bilateral salpingo-oophorectomy (BSO ...

In women with BRCA1 mutations, hormonal contraceptives were associated with a significantly higher risk for breast cancer in a dose-response relationship, researchers reported in an observational ...