The most prominent players are the BRCA1 (Chromosome 17) and BRCA2 (Chromosome 13) genes, which are responsible for repairing DNA damage. Transmutations in these genes, often passed down through ...
The authors suggest that the loss of chromosome 17 offers a potential explanation for the concurrent inactivation of both the TP53 and BRCA1 genes, which are both located on chromosome 17 and ...