Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

Even two women with the same cancer gene mutation—such as the 185delAG mutation of BRCA1 found in the Hispanic women featured in "The Secret of San Luis Valley"—may experience very different ...

The research, published in Nature Genetics, shows that even in the absence of a second mutational hit, a single faulty copy of BRCA1 renders breast cells more vulnerable to cancer and is ...