A baclofen withdrawal syndrome can occur with rapid cessation of usage. Withdrawal symptoms include a rebound increase in spasticity, fever, altered mental status, seizures, malignant hyperthermia ...

The pump is programmed using a surface tablet to deliver specified baclofen doses throughout the day. Baclofen withdrawal can occur with delayed refills, erroneous programming, or pump or catheter ...

Xu and colleagues, therefore, conducted a randomized, double-blind, placebo-controlled crossover study to evaluate the efficacy of baclofen, a potent γ-aminobutyric acid receptor agonist ...