Researchers uncover why the body may keep reacting to a hidden threat even long after the bacteria are gone. As many as 20 ...

Jack Strominger recounts his seminal work and contributions to understanding bacterial cell wall components ... I meant an antibody reaction—against peptidoglycan. My knowledge of immunology ...

Scientists believe they know what causes the treated infection to mimic chronic illness: the body may be responding to remnants of the bacteria that causes Lyme that tend to pool in the liver and ...

As the bacteria grow, they spit out peptidoglycan, a component of the cell wall that acts like a large molecular bag. These remnants can still cause inflammation if injected into healthy mice.

Tying the two studies together is the fact that piperacillin is a broad-spectrum antibiotic that interferes with the synthesis of peptidoglycan, an essential part of the bacterial cell wall. Both ...

and enzymes MraY and MurF involved in bacterial peptidoglycan assembly. In 1997, Tim wrote the textbook Introduction to Enzyme and Coenzyme Chemistry, which is used in undergraduate chemistry courses ...

In a nutshell The antibiotic piperacillin has shown remarkable effectiveness against Lyme disease-causing bacteria, Borrelia ...

We use the infamous “super bug” Staphylococcus aureus as our target organism to address key fundamental questions of bacterial life and death. S. aureus cell wall synthesis at the molecular level: ...

My work is focused on the study of the bacterial cell wall using essentially two Gram-positive pathogens (Staphylococcus aureus, Enterococcus faecalis) as models. I am interested in three major areas ...