Pain signals originating in the body’s periphery are conveyed to the brain along a relay of neurons in four different parts of the ascending sensory pathway: the dorsal root ganglion, dorsal ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

The human body relies on three kinds of opioid receptors to regulate pain, much like traffic control systems on a busy highway. Understanding these pathways is key to developing safer pain treatments.

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top ...