He started by trying to conditionally remove a protease that was specific to basophils. Luckily, the engineered mice were unable to make basophils at all, thus providing the researchers with a model ...

The basophil activation test (BAT) is not a primary diagnostic tool; it is a test complementary to the skin test and quantification of allergen-specific IgE. The BAT is currently mostly applied in ...

we established basophil-specific TTP-knockout mice and evaluated the severity of allergic inflammation using an oxazolone-induced atopic dermatitis model." The study revealed that TTP plays a ...