Apoptosis occurs in a wide range of human ... The effector molecules, such as BCL-2 associated x protein (BAX) and BCL-2 antagonist killer 1 (BAK1), contain BH domains 1–3 and permeabilize ...

研究人员分析 118 例孕妇胎盘样本，发现 Bax 和 Bcl-2 表达与分娩及 PROM 相关，为胎盘研究提供新视角。 在孕期，胎盘可是至关重要的器官，它的发育状况直接关乎胎儿的健康。胎盘功能障碍与多种孕期并发症密切相关，比如早产、胎儿生长受限以及胎膜早破（PROM ...

and change in the mRNA levels of BCL-2/Bax, PTEN, and CDK4 as a consequence of MYC downregulation. Moreover, the researchers analyzed the effects of miR-377 on apoptosis, proliferation ...