Mix beads, fully resuspend Have enough beads : ~35 ul per sample Make 75% ethanol (400 ul per cleanup) : 1,125 ul ethanol, 375 water = 1.5 ml Binding: For x vol DNA, add ==1.5x vol of beads== (See ...

In other words, a piece of DNA that is 1 meter long will become a "string-of-beads" chromatin fiber just 14 centimeters (about 6 inches) long. Despite this shortening, a half-foot of chromatin is ...