Piperacillin, an antibiotic in the same class as penicillin, effectively cured mice of Lyme disease at 100-times less than the effective dose of doxycycline, the current gold standard treatment. At ...

A Northwestern University study reveals that piperacillin, a common antibiotic, effectively treats Lyme disease in mice at a ...

Lyme disease, a disease transmitted when deer ticks feed on infected animals like deer and rodents, and then bite humans, impacts nearly half a million individuals in the U.S. annually.

The drug – a combination of beta-lactam antibiotic aztreonam with beta-lactamase inhibitor avibactam – is the first monobactam/β-lactamase inhibitor combination to be cleared in the US for ...

Beta-lactamase inhibitors are designed to overcome a key resistance mechanism that allows pathogens to protect themselves from beta-lactams, one of the most commonly-used antibiotic classes.

is one of the major mechanisms of antibiotic resistance. Plasmid borne genes encoding modifying enzymes such as beta-lactamases, that confer resistance to penicillins and related antibiotics, or, more ...

Iterum Therapeutics plc (Nasdaq: ITRM), a company focused on delivering next generation oral and IV antibiotics to treat infections caused by multi-drug resistant pathogens in both community and ...

A long-term research interest of the Palzkill lab is the use of genetic and biochemical approaches to study the structure, function and evolution of antibiotic resistance enzymes. A particular focus ...

This rate is higher than observed in children treated with a beta-lactamase resistant agent ... on factors that may have influenced choice of antibiotic agent or on treatment compliance.