Among children treated with an oral agent, the recurrence rate was 16/42 (38.1%) following penicillin or amoxicillin and 10/36 (27.8%) following a beta-lactamase resistant agent (adjusted odds ...

the biologic effect of the combination would be greater than the sum of the individual effects. Four requirements for synergy by competititive inhibition of a β-lactamase have been demonstrated ...

Among the 26 patients who had at least 1 recurrence, early symptoms developed in 11 (68.8%) of 16 treated with amoxicillin or penicillin and in 5 (50.0%) of 10 treated with a beta-lactamase ...

that may inactivate certain beta-lactamase enzymes. Take with meals. Base dose on amoxicillin component. Due to clavulanic acid component: two 250mg tabs are not equivalent to one 500mg tab.