This paper considers the question of an antedating lupus diathesis in the hydralazine syndrome and of its reversibility upon discontinuation of treatment with the drug. The data on 50 patients ...

MANY drugs have been reported to induce a syndrome resembling systemic lupus erythematosus. These include hydralazine, 1–6 penicillin, 7,8 phenylbutazone, 9 sulfadiazine, 10,11 methylphenyl ...

For people treated for one to two years at currently used doses of the high-risk drugs, approximately 5% of those taking hydralazine and 20% of those taking procainamide will develop drug-induced ...