How did you discover MCBAs? Bile acids were first described chemically in 1849, and Heinrich Wieland was awarded a Nobel Prize in 1927 for comprehensively describing their chemistry. This ...

As well as having a role in lipid absorption, bile acids can act as endocrine-signaling molecules. With previous studies suggesting that bile acids operate as metabolic integrators, Watanabe et al.

Blocking YAP's repressor activity—either by enhancing FXR function or promoting bile acid excretion—could stop this damaging cycle, according to researchers. In experimental models, activating ...

A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of pro-inflammatory T helper ...

They found that in UC patients, the lower levels of 7α-dehydroxylated bile acids strongly correlated with impaired intestinal ...