The gold standard technology that scientists use to detect DNA methylation is bisulfite genomic sequencing. It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at ...

Using machine learning algorithms and deep whole-genome bisulfite sequencing on freshly isolated and purified cell populations, the study unveils a detailed landscape of genetic and epigenetic ...

Chromatin immunoprecipitation sequencing allows for genome-wide profiling of protein-DNA interactions and of histone PTMs. GARP offers ChIP-seq library construction starting with ChIP and Input DNA.

Sequence context is an important control because bisulfite-treated, PCR-amplified DNA is A-T-rich, which decreases sequence variation. Pyro Q-CpG therefore guarantees that the correct sequence was ...