Yamada et al. evaluated the performance of serum tartrate-resistant acid phosphatase 5b (TRACP5b), a biochemical marker for bone resorption, in comparison with established markers in the ...

“Our findings suggest that injectable hydrogels with localized anti-catabolic drug delivery can complement systemic ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

Strong, dense bones result from a balance between bone breakdown (resorption) and bone formation. A disruption in the interplay between the bone-building osteoblast cells and the bone-degrading ...

which are responsible for bone resorption to initiate normal bone remodeling,” Mohanakrishnan continues. The researchers showed that these Type R capillaries contribute to the oxygenation of hypoxic ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

which are responsible for bone resorption. Until now, it has not been understood how these cells function in the low-oxygen microenvironment of bone. Researchers at the Max Planck Institute for ...

Researchers have identified Type R capillaries’ importance in bone remodelling in mature and ageing bones. This shows that ...

A new study reveals that iSN40 also inhibits osteoclastogenesis, reducing bone resorption. By modulating both bone formation and resorption, iSN40 offers a potential new approach for the treatment ...

Osteoporosis is a disease in which bone resorbs faster than it is formed, gradually weakening its structure over time and ...

Bone is constantly being remodeled through a process of resorption, in which old bone tissue is removed by osteoclasts, and formation, in which the old bone tissue is replaced with new tissue ...

Sr incorporation in PEEK via a polydopamine coating improves osteogenic potential, promoting cell adhesion and mineralization ...