多发性骨髓瘤（MM）难以治愈且易复发，骨髓微环境中免疫抑制细胞影响免疫治疗效果。研究人员探究 MM 中骨髓 CD14+单核细胞抑制 T 淋巴细胞的机制，发现相关异常及 ULK2 作用，为理解免疫抑制环境、改善免疫治疗提供依据。

LPS receptor-deleted mice (i.e., CD14 mutants) are hypersensitive to insulin, and the occurrence of insulin resistance, obesity, and diabetes is delayed in response to high-fat feeding.

Chronic lymphocytic leukemia (CLL) cell–derived exosomes demonstrated the ability to alter healthy donor cell function and suppress normal blood cell formation. These particles affected monocytes, ...