In addition, the association of CD3 with the TCR–peptide–MHC complex transmits the activation signal to intracellular signalling molecules to initiate a signalling cascade in the T cell.

DelveInsight’s Non-Hodgkin Lymphoma pipeline report depicts a robust space with 200+ Non-Hodgkin Lymphoma companies working ...

Interleukins are cytokines produced and secreted mainly by CD3+ and CD4+ T lymphocytes ... of oxidative phosphorylation and hypoxia via signaling in non-hematopoietic cells.

Multiple studies have now demonstrated that 4-1BBL can independently provide co-stimulatory signals to induce T cell proliferation, separate from CD28 molecule signaling. Our other products for T cell ...

CD20 × CD3 bispecific antibodies bind to both CD20 on malignant B cells and CD3 on T cells, bringing them into close proximity, which triggers T cell-mediated killing of the targeted B cells.